Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS

Clinical investigations have demonstrated that polycystic ovary syndrome (PCOS) is often accompanied by insulin resistance (IR) in more than 70% of women with PCOS. However, the etiology of PCOS with IR remains to be characterized. Growth differentiation factor 8 (GDF8) is an intraovarian factor tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Bai, Long, Wang, Wei, Xiang, Yu, Wang, Shuyi, Wan, Shan, Zhu, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779537/
https://www.ncbi.nlm.nih.gov/pubmed/33425488
http://dx.doi.org/10.1016/j.omtn.2020.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779537/
https://www.ncbi.nlm.nih.gov/pubmed/33425488
http://dx.doi.org/10.1016/j.omtn.2020.11.005

Ejemplares similares