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Ethylene glycol poisoning: A diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis
INTRODUCTION: Due to the nationwide lockdown to mitigate the spread of COVID-19 and subsequent alcohol ban in South Africa, several cases of toxic alcohol ingestion presented to our emergency unit. Many of these patients admitted to making home brews of alcohol while others simply use industrial tox...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
African Federation for Emergency Medicine
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779712/ https://www.ncbi.nlm.nih.gov/pubmed/33425670 http://dx.doi.org/10.1016/j.afjem.2020.10.011 |
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author | Smit, Almien Lalloo, Vidya Engelbrecht, Andreas |
author_facet | Smit, Almien Lalloo, Vidya Engelbrecht, Andreas |
author_sort | Smit, Almien |
collection | PubMed |
description | INTRODUCTION: Due to the nationwide lockdown to mitigate the spread of COVID-19 and subsequent alcohol ban in South Africa, several cases of toxic alcohol ingestion presented to our emergency unit. Many of these patients admitted to making home brews of alcohol while others simply use industrial toxic alcohols. The diagnosis of these poisonings is challenging as direct assays are not available in our setting. CASE REPORT: We present a case of presumed ethylene glycol poisoning that presented with persistent seizures and a high anion gap metabolic acidosis (HAGMA). DISCUSSION: A high index of suspicion for toxic alcohol poisoning should be maintained in patients presenting with an altered mental status, seizures and a HAGMA. Indirect markers such as clinical features and laboratory results can lead to the diagnosis when direct assays are unavailable. |
format | Online Article Text |
id | pubmed-7779712 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | African Federation for Emergency Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-77797122021-01-08 Ethylene glycol poisoning: A diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis Smit, Almien Lalloo, Vidya Engelbrecht, Andreas Afr J Emerg Med Case Report INTRODUCTION: Due to the nationwide lockdown to mitigate the spread of COVID-19 and subsequent alcohol ban in South Africa, several cases of toxic alcohol ingestion presented to our emergency unit. Many of these patients admitted to making home brews of alcohol while others simply use industrial toxic alcohols. The diagnosis of these poisonings is challenging as direct assays are not available in our setting. CASE REPORT: We present a case of presumed ethylene glycol poisoning that presented with persistent seizures and a high anion gap metabolic acidosis (HAGMA). DISCUSSION: A high index of suspicion for toxic alcohol poisoning should be maintained in patients presenting with an altered mental status, seizures and a HAGMA. Indirect markers such as clinical features and laboratory results can lead to the diagnosis when direct assays are unavailable. African Federation for Emergency Medicine 2021-03 2020-11-06 /pmc/articles/PMC7779712/ /pubmed/33425670 http://dx.doi.org/10.1016/j.afjem.2020.10.011 Text en © 2018 Published by Elsevier Ltd. CC BY-NC-ND 4.0. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Smit, Almien Lalloo, Vidya Engelbrecht, Andreas Ethylene glycol poisoning: A diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis |
title | Ethylene glycol poisoning: A diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis |
title_full | Ethylene glycol poisoning: A diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis |
title_fullStr | Ethylene glycol poisoning: A diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis |
title_full_unstemmed | Ethylene glycol poisoning: A diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis |
title_short | Ethylene glycol poisoning: A diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis |
title_sort | ethylene glycol poisoning: a diagnostic challenge in a patient with persistent seizures and a severe metabolic acidosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779712/ https://www.ncbi.nlm.nih.gov/pubmed/33425670 http://dx.doi.org/10.1016/j.afjem.2020.10.011 |
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