Cargando…
Tryptophanyl-tRNA Synthetase Sensitizes Hormone Receptor-Positive Breast Cancer to Docetaxel-Based Chemotherapy
PURPOSE: A relatively low response to chemotherapy has been reported for hormone receptor (HR)-positive breast cancer. In this study, we investigated the role of tryptophanyl-transfer RNA synthetase (WARS) in the chemotherapeutic response of HR-positive breast cancer. METHODS: Pre-chemotherapeutic n...
Autores principales: | Lee, Kyung-Min, Hwang, Eun Hye, Kang, Seong Eun, Lee, Cheng Hyun, Lee, Hyebin, Oh, Hyeon Jeong, Kim, Kwangsoo, Koh, Jiwon, Ryu, Han Suk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Breast Cancer Society
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779724/ https://www.ncbi.nlm.nih.gov/pubmed/33408886 http://dx.doi.org/10.4048/jbc.2020.23.e67 |
Ejemplares similares
-
Tryptophanyl-tRNA Synthetase as a Potential Therapeutic Target
por: Ahn, Young Ha, et al.
Publicado: (2021) -
Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase
por: Dong, Xianchi, et al.
Publicado: (2010) -
Structure of a tryptophanyl-tRNA synthetase containing an iron–sulfur cluster
por: Han, Gye Won, et al.
Publicado: (2010) -
Overexpressed tryptophanyl-tRNA synthetase, an angiostatic protein, enhances oral cancer cell invasiveness
por: Lee, Chien-Wei, et al.
Publicado: (2015) -
Combined the SMAC mimetic and BCL2 inhibitor sensitizes neoadjuvant chemotherapy by targeting necrosome complexes in tyrosine aminoacyl-tRNA synthase-positive breast cancer
por: Lee, Kyung-Min, et al.
Publicado: (2020)