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Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy

Background: To evaluate the efficacy, safeness and cost of ultrasound-guided local lauromacrogol injection (USG-LLI) combined with curettage and hysteroscopy for cesarean scar pregnancy (CSP). Methods: This was a retrospective study included 151 CSP patients diagnosed with CSP from June 2017 to Dece...

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Autores principales: Wu, Qing, Liu, Xia, Zhu, Lin, Zhu, Yichen, Mei, Tingting, Cao, Shanshan, Shen, Yan, Ding, Jun, Lin, Tan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779759/
https://www.ncbi.nlm.nih.gov/pubmed/33408631
http://dx.doi.org/10.3389/fphar.2020.601977
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author Wu, Qing
Liu, Xia
Zhu, Lin
Zhu, Yichen
Mei, Tingting
Cao, Shanshan
Shen, Yan
Ding, Jun
Lin, Tan
author_facet Wu, Qing
Liu, Xia
Zhu, Lin
Zhu, Yichen
Mei, Tingting
Cao, Shanshan
Shen, Yan
Ding, Jun
Lin, Tan
author_sort Wu, Qing
collection PubMed
description Background: To evaluate the efficacy, safeness and cost of ultrasound-guided local lauromacrogol injection (USG-LLI) combined with curettage and hysteroscopy for cesarean scar pregnancy (CSP). Methods: This was a retrospective study included 151 CSP patients diagnosed with CSP from June 2017 to December 2019, and treated by USG-LLI (n = 86) or uterine artery embolization (UAE) (n = 65) combined with curettage and hysteroscopy. Clinical data and outcome were analyzed. Results: There were no significant differences in basic clinical characteristics in the two groups. Two groups showed the similar success rates. USG-LLI group, compared with UAE group had significantly lower complication rates (9.30 vs. 44.62%), lower total costs (both medical and non-medication cost) (p < 0.05). Conclusions: USG-LLI combined with curettage and hysteroscopy is a feasible method to treat CSP with minimal invasion and high efficacy. Moreover, compared with curettage after UAE, USG-LLI exhibited lower complication rate and required fewer expenses.
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spelling pubmed-77797592021-01-05 Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy Wu, Qing Liu, Xia Zhu, Lin Zhu, Yichen Mei, Tingting Cao, Shanshan Shen, Yan Ding, Jun Lin, Tan Front Pharmacol Original Research Background: To evaluate the efficacy, safeness and cost of ultrasound-guided local lauromacrogol injection (USG-LLI) combined with curettage and hysteroscopy for cesarean scar pregnancy (CSP). Methods: This was a retrospective study included 151 CSP patients diagnosed with CSP from June 2017 to December 2019, and treated by USG-LLI (n = 86) or uterine artery embolization (UAE) (n = 65) combined with curettage and hysteroscopy. Clinical data and outcome were analyzed. Results: There were no significant differences in basic clinical characteristics in the two groups. Two groups showed the similar success rates. USG-LLI group, compared with UAE group had significantly lower complication rates (9.30 vs. 44.62%), lower total costs (both medical and non-medication cost) (p < 0.05). Conclusions: USG-LLI combined with curettage and hysteroscopy is a feasible method to treat CSP with minimal invasion and high efficacy. Moreover, compared with curettage after UAE, USG-LLI exhibited lower complication rate and required fewer expenses. Frontiers Media S.A. 2020-12-21 /pmc/articles/PMC7779759/ /pubmed/33408631 http://dx.doi.org/10.3389/fphar.2020.601977 Text en Copyright © 2020 Lin, Wu, Zhu, Zhu, Mei, Liu, Cao, Shen and Ding http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (http://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Original Research
Wu, Qing
Liu, Xia
Zhu, Lin
Zhu, Yichen
Mei, Tingting
Cao, Shanshan
Shen, Yan
Ding, Jun
Lin, Tan
Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy
title Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy
title_full Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy
title_fullStr Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy
title_full_unstemmed Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy
title_short Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy
title_sort clinical assessment of ultrasound-guided local lauromacrogol injection combined with curettage and hysteroscopy for cesarean scar pregnancy
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779759/
https://www.ncbi.nlm.nih.gov/pubmed/33408631
http://dx.doi.org/10.3389/fphar.2020.601977
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