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Proteolysis of Rab32 by Salmonella GtgE induces an inactive GTPase conformation
Rab GTPases are central regulators of intracellular vesicular trafficking. They are frequently targeted by bacterial pathogens through post-translational modifications. Salmonella typhimurium secretes the cysteine protease GtgE during infection, leading to a regioselective proteolytic cleavage of th...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779776/ https://www.ncbi.nlm.nih.gov/pubmed/33426511 http://dx.doi.org/10.1016/j.isci.2020.101940 |