The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDA) initiation and progression are accompanied by an immunosuppressive inflammatory response. Here, we evaluated the immunomodulatory role of chemosensory signaling in metaplastic tuft cells (MTCs) by analyzing the role of GNAT3, a gustatory...

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Detalles Bibliográficos
Autores principales: Hoffman, Megan T., Kemp, Samantha B., Salas-Escabillas, Daniel J., Zhang, Yaqing, Steele, Nina G., The, Stephanie, Long, Daniel, Benitz, Simone, Yan, Wei, Margolskee, Robert F., Bednar, Filip, Pasca di Magliano, Marina, Wen, Hui-Ju, Crawford, Howard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779788/
https://www.ncbi.nlm.nih.gov/pubmed/32882403
http://dx.doi.org/10.1016/j.jcmgh.2020.08.011

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