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The Role of Orai1 in Regulating Sarcoplasmic Calcium Release, Mitochondrial Morphology and Function in Myostatin Deficient Skeletal Muscle

In mice a naturally occurring 12-bp deletion in the myostatin gene is considered responsible for the compact phenotype (Mstn(Cmpt–dl1Abc), Cmpt) labeled by a tremendous increase in body weight along with signs of muscle weakness, easier fatigability, decreased Orai1 expression and store operated cal...

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Detalles Bibliográficos
Autores principales: Sztretye, Mónika, Singlár, Zoltán, Balogh, Norbert, Kis, Gréta, Szentesi, Péter, Angyal, Ágnes, Balatoni, Ildikó, Csernoch, László, Dienes, Beatrix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779810/
https://www.ncbi.nlm.nih.gov/pubmed/33408641
http://dx.doi.org/10.3389/fphys.2020.601090