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FMS‐like tyrosine kinase 3 (FLT3) amplification in patients with metastatic colorectal cancer

FMS‐like tyrosine kinase 3 (FLT3) plays a key role in hematopoiesis. However, the oncogenic role of FLT3 amplification in patients with metastatic colorectal cancer (mCRC) remains unclear. Here, we aimed to evaluate the characteristics, prognosis, and treatment efficacy of an FLT3 inhibitor (regoraf...

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Detalles Bibliográficos
Autores principales: Hasegawa, Hiroko, Taniguchi, Hiroya, Nakamura, Yoshiaki, Kato, Takeshi, Fujii, Satoshi, Ebi, Hiromichi, Shiozawa, Manabu, Yuki, Satoshi, Masuishi, Toshiki, Kato, Ken, Izawa, Naoki, Moriwaki, Toshikazu, Oki, Eiji, Kagawa, Yoshinori, Denda, Tadamichi, Nishina, Tomohiro, Tsuji, Akihito, Hara, Hiroki, Esaki, Taito, Nishida, Tomohiro, Kawakami, Hisato, Sakamoto, Yasutoshi, Miki, Izumi, Okamoto, Wataru, Yamazaki, Kentaro, Yoshino, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780005/
https://www.ncbi.nlm.nih.gov/pubmed/33075166
http://dx.doi.org/10.1111/cas.14693