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The role of Hippo‐YAP signaling in squamous cell carcinomas

The Hippo‐YAP pathway regulates organ size, tissue homeostasis, and tumorigenesis in mammals. In response to cell density, external mechanical pressure, and/or other stimuli, the Hippo core complex controls the translocation of YAP1/TAZ proteins to the nucleus and thereby regulates cell growth. Abno...

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Detalles Bibliográficos
Autores principales: Maehama, Tomohiko, Nishio, Miki, Otani, Junji, Mak, Tak Wah, Suzuki, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780025/
https://www.ncbi.nlm.nih.gov/pubmed/33159406
http://dx.doi.org/10.1111/cas.14725