CD24, not CD47, negatively impacts upon response to PD‐1/L1 inhibitors in non–small‐cell lung cancer with PD‐L1 tumor proportion score < 50

CD24, a heavily glycosylated glycosylphosphatidylinositol–anchored surface protein, inhibits phagocytosis as potently as CD47. The relationship between such anti‐phagocytic factors and the immune response with immune–checkpoint inhibitors (ICI) remains unexplored. We evaluated CD24 and CD47 tumor pr...

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Detalles Bibliográficos
Autores principales: Ozawa, Yuichi, Harutani, Yuhei, Oyanagi, Jun, Akamatsu, Hiroaki, Murakami, Eriko, Shibaki, Ryota, Hayata, Atsushi, Sugimoto, Takeya, Tanaka, Masanori, Takakura, Toshiaki, Furuta, Katsuyuki, Okuda, Yuka, Sato, Kouichi, Teraoka, Shunsuke, Ueda, Hiroki, Tokudome, Nahomi, Kitamura, Yuka, Fukuoka, Junya, Nakanishi, Masanori, Koh, Yasuhiro, Yamamoto, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Basic and Clinical Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780034/
https://www.ncbi.nlm.nih.gov/pubmed/33084148
http://dx.doi.org/10.1111/cas.14705

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