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Development of an activity assay for characterizing deoxyhypusine synthase and its diverse reaction products

Deoxyhypusine synthase transfers an aminobutyl moiety from spermidine to the eukaryotic translation initiation factor 5A (eIF5A) in the first step of eIF5A activation. This exclusive post‐translational modification is conserved in all eukaryotes. Activated eIF5A has been shown to be essential for ce...

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Detalles Bibliográficos
Autores principales:	Kaltenegger, Elisabeth, Prakashrao, Arunraj S., Çiçek, Serhat S., Ober, Dietrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780104/ https://www.ncbi.nlm.nih.gov/pubmed/33247548 http://dx.doi.org/10.1002/2211-5463.13046

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