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Spatiotemporal immunolocalisation of REST in the brain of healthy ageing and Alzheimer’s disease rats
In the brain, REST (Repressor Element‐1 Silencing Transcription factor) is a key regulator of neuron cell‐specific gene expression. Nuclear translocation of neuronal REST has been shown to be neuroprotective in a healthy ageing context. In contrast, inability to upregulate nuclear REST is thought to...
Autores principales: | Mampay, Myrthe, Velasco‐Estevez, María, Rolle, Sara O., Chaney, Aisling M., Boutin, Hervé, Dev, Kumlesh K., Moeendarbary, Emad, Sheridan, Graham K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780110/ https://www.ncbi.nlm.nih.gov/pubmed/33185010 http://dx.doi.org/10.1002/2211-5463.13036 |
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