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miR‐34a‐5p up‐regulates the IL‐1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons

Migraine is a debilitating neurological condition, with a global prevalence rate of 10.68% in men and 18.79% in women. Elucidation of the molecular mechanisms underlying migraines is of great importance for improving the quality of life of patients. The release of the neuropeptide calcitonin gene‐re...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Zhang, Xue‐mei, Zong, Dan‐dan, Ji, Xiao‐ying, Jiang, Hua, Zhang, Feng‐zheng, He, Sheng‐dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780114/
https://www.ncbi.nlm.nih.gov/pubmed/33155431
http://dx.doi.org/10.1002/2211-5463.13027

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