Cargando…
Efficacy and safety of nitazoxanide plus atazanavir/ritonavir for the treatment of moderate to severe COVID-19 (NACOVID): A structured summary of a study protocol for a randomised controlled trial
OBJECTIVES: To investigate the efficacy and safety of repurposed antiprotozoal and antiretroviral drugs, nitazoxanide and atazanavir/ritonavir, in shortening the time to clinical improvement and achievement of SARS-CoV-2 polymerase chain reaction (PCR) negativity in patients diagnosed with moderate...
Autores principales: | Olagunju, Adeniyi, Fowotade, Adeola, Olagunoye, Ajibola, Ojo, Temitope Olumuyiwa, Adefuye, Bolanle Olufunlola, Fagbamigbe, Adeniyi Francis, Adebiyi, Akindele Olupelumi, Olagunju, Omobolanle Ibitayo, Ladipo, Olabode Taiwo, Akinloye, Abdulafeez, Adeagbo, Babatunde Ayodeji, Onayade, Adedeji, Bolaji, Oluseye Oladotun, Happi, Christian, Rannard, Steve, Owen, Andrew |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780204/ https://www.ncbi.nlm.nih.gov/pubmed/33397457 http://dx.doi.org/10.1186/s13063-020-04987-8 |
Ejemplares similares
-
A randomized, open-label trial of combined nitazoxanide and atazanavir/ritonavir for mild to moderate COVID-19
por: Fowotade, Adeola, et al.
Publicado: (2022) -
Validation and Clinical Application of a Liquid Chromatography-Ultraviolet Detection Method to Quantify Dolutegravir in Dried Blood Spots
por: Akinloye, Abdulafeez, et al.
Publicado: (2022) -
Mechanistic Modeling of Maternal Lymphoid and Fetal Plasma Antiretroviral Exposure During the Third Trimester
por: Shenkoya, Babajide, et al.
Publicado: (2021) -
Use of a physiologically-based pharmacokinetic model to simulate artemether dose adjustment for overcoming the drug-drug interaction with efavirenz
por: Siccardi, Marco, et al.
Publicado: (2013) -
Using mechanistic physiologically-based pharmacokinetic models to assess prenatal drug exposure: Thalidomide versus efavirenz as case studies
por: Atoyebi, Shakir Adeyinka, et al.
Publicado: (2019)