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Structures of ISC th4 transpososomes reveal the role of asymmetry in copy‐out/paste‐in DNA transposition

Copy‐out/paste‐in transposition is a major bacterial DNA mobility pathway. It contributes significantly to the emergence of antibiotic resistance, often by upregulating expression of downstream genes upon integration. Unlike other transposition pathways, it requires both asymmetric and symmetric str...

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Detalles Bibliográficos
Autores principales: Kosek, Dalibor, Hickman, Alison B, Ghirlando, Rodolfo, He, Susu, Dyda, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780238/
https://www.ncbi.nlm.nih.gov/pubmed/33006208
http://dx.doi.org/10.15252/embj.2020105666