Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers due to its high metastasis rate in the liver. However, little is known about the molecular features of hepatic metastases due to difficulty in obtaining fresh tissues and low tumor cellularity. RESULTS: We conduct...

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Detalles Bibliográficos
Autores principales: Yang, Jianyu, Lin, Ping, Yang, Minwei, Liu, Wei, Fu, Xueliang, Liu, Dejun, Tao, Lingye, Huo, Yanmiao, Zhang, Junfeng, Hua, Rong, Zhang, Zhigang, Li, Yixue, Wang, Liwei, Xue, Jing, Li, Hong, Sun, Yongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780398/
https://www.ncbi.nlm.nih.gov/pubmed/33397441
http://dx.doi.org/10.1186/s13059-020-02222-w

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