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Chest X-ray in the emergency department during COVID-19 pandemic descending phase in Italy: correlation with patients’ outcome

PURPOSE: The aims of our study are: (1) to estimate admission chest X-ray (CXR) accuracy during the descending phase of pandemic; (2) to identify specific CXR findings strictly associated with COVID-19 infection; and (3) to correlate lung involvement of admission CXR with patients’ outcome. MATERIAL...

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Autores principales: Moroni, Chiara, Cozzi, Diletta, Albanesi, Marco, Cavigli, Edoardo, Bindi, Alessandra, Luvarà, Silvia, Busoni, Simone, Mazzoni, Lorenzo Nicola, Grifoni, Stefano, Nazerian, Peiman, Miele, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780606/
https://www.ncbi.nlm.nih.gov/pubmed/33394364
http://dx.doi.org/10.1007/s11547-020-01327-3
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author Moroni, Chiara
Cozzi, Diletta
Albanesi, Marco
Cavigli, Edoardo
Bindi, Alessandra
Luvarà, Silvia
Busoni, Simone
Mazzoni, Lorenzo Nicola
Grifoni, Stefano
Nazerian, Peiman
Miele, Vittorio
author_facet Moroni, Chiara
Cozzi, Diletta
Albanesi, Marco
Cavigli, Edoardo
Bindi, Alessandra
Luvarà, Silvia
Busoni, Simone
Mazzoni, Lorenzo Nicola
Grifoni, Stefano
Nazerian, Peiman
Miele, Vittorio
author_sort Moroni, Chiara
collection PubMed
description PURPOSE: The aims of our study are: (1) to estimate admission chest X-ray (CXR) accuracy during the descending phase of pandemic; (2) to identify specific CXR findings strictly associated with COVID-19 infection; and (3) to correlate lung involvement of admission CXR with patients’ outcome. MATERIALS AND METHODS: We prospectively evaluated the admission CXR of 327 patients accessed to our institute during the Italian pandemic descending phase (April 2020). For each CXR were searched ground glass opacification (GGO), consolidation (CO), reticular-nodular opacities (RNO), nodules, excavations, pneumothorax, pleural effusion, vascular congestion and cardiac enlargement. For lung alterations was defined the predominance (upper or basal, focal or diffuse, central or peripheric, etc.). Then radiologists assessed whether CXRs were suggestive or not for COVID-19 infection. For COVID-19 patients, a prognostic score was applied and correlated with the patients’ outcome. RESULTS: CXR showed 83% of specificity and 60% of sensitivity. GGO, CO, RNO and a peripheric, diffuse and basal prevalence showed good correlation with COVID-19 diagnosis. A logistic regression analysis pointed out GGO and a basal or diffuse distribution as independent predictors of COVID-19 diagnosis. The prognostic score showed good correlation with the patients’ outcome. CONCLUSION: In our study, admission CXR showed a fair specificity and a good correlation with patients’ outcome. GGO and others CXR findings showed a good correlation with COVID-19 diagnosis; besides GGO a diffuse or bibasal distribution resulted in independent variables highly suggestive for COVID-19 infection thus enabling radiologists to signal to clinicians radiologically suspect patients during the pandemic descending phase.
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spelling pubmed-77806062021-01-05 Chest X-ray in the emergency department during COVID-19 pandemic descending phase in Italy: correlation with patients’ outcome Moroni, Chiara Cozzi, Diletta Albanesi, Marco Cavigli, Edoardo Bindi, Alessandra Luvarà, Silvia Busoni, Simone Mazzoni, Lorenzo Nicola Grifoni, Stefano Nazerian, Peiman Miele, Vittorio Radiol Med Chest Radiology PURPOSE: The aims of our study are: (1) to estimate admission chest X-ray (CXR) accuracy during the descending phase of pandemic; (2) to identify specific CXR findings strictly associated with COVID-19 infection; and (3) to correlate lung involvement of admission CXR with patients’ outcome. MATERIALS AND METHODS: We prospectively evaluated the admission CXR of 327 patients accessed to our institute during the Italian pandemic descending phase (April 2020). For each CXR were searched ground glass opacification (GGO), consolidation (CO), reticular-nodular opacities (RNO), nodules, excavations, pneumothorax, pleural effusion, vascular congestion and cardiac enlargement. For lung alterations was defined the predominance (upper or basal, focal or diffuse, central or peripheric, etc.). Then radiologists assessed whether CXRs were suggestive or not for COVID-19 infection. For COVID-19 patients, a prognostic score was applied and correlated with the patients’ outcome. RESULTS: CXR showed 83% of specificity and 60% of sensitivity. GGO, CO, RNO and a peripheric, diffuse and basal prevalence showed good correlation with COVID-19 diagnosis. A logistic regression analysis pointed out GGO and a basal or diffuse distribution as independent predictors of COVID-19 diagnosis. The prognostic score showed good correlation with the patients’ outcome. CONCLUSION: In our study, admission CXR showed a fair specificity and a good correlation with patients’ outcome. GGO and others CXR findings showed a good correlation with COVID-19 diagnosis; besides GGO a diffuse or bibasal distribution resulted in independent variables highly suggestive for COVID-19 infection thus enabling radiologists to signal to clinicians radiologically suspect patients during the pandemic descending phase. Springer Milan 2021-01-04 2021 /pmc/articles/PMC7780606/ /pubmed/33394364 http://dx.doi.org/10.1007/s11547-020-01327-3 Text en © Italian Society of Medical Radiology 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Chest Radiology
Moroni, Chiara
Cozzi, Diletta
Albanesi, Marco
Cavigli, Edoardo
Bindi, Alessandra
Luvarà, Silvia
Busoni, Simone
Mazzoni, Lorenzo Nicola
Grifoni, Stefano
Nazerian, Peiman
Miele, Vittorio
Chest X-ray in the emergency department during COVID-19 pandemic descending phase in Italy: correlation with patients’ outcome
title Chest X-ray in the emergency department during COVID-19 pandemic descending phase in Italy: correlation with patients’ outcome
title_full Chest X-ray in the emergency department during COVID-19 pandemic descending phase in Italy: correlation with patients’ outcome
title_fullStr Chest X-ray in the emergency department during COVID-19 pandemic descending phase in Italy: correlation with patients’ outcome
title_full_unstemmed Chest X-ray in the emergency department during COVID-19 pandemic descending phase in Italy: correlation with patients’ outcome
title_short Chest X-ray in the emergency department during COVID-19 pandemic descending phase in Italy: correlation with patients’ outcome
title_sort chest x-ray in the emergency department during covid-19 pandemic descending phase in italy: correlation with patients’ outcome
topic Chest Radiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780606/
https://www.ncbi.nlm.nih.gov/pubmed/33394364
http://dx.doi.org/10.1007/s11547-020-01327-3
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