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Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis
BACKGROUND: Variants in CDKN2B/CDKN2B-AS1 have been reported to modulate glaucoma risk in several GWAS across different populations. CDKN2B/CDKN2A encodes tumor suppressor proteins p16(INK4A)/p15(INK4B) which influences cell proliferation/senescence in RGCs, the degeneration of which is a risk facto...
Autores principales: | Thakur, Nanamika, Kupani, Manu, Mannan, Rashim, Pruthi, Archna, Mehrotra, Sanjana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780652/ https://www.ncbi.nlm.nih.gov/pubmed/33397358 http://dx.doi.org/10.1186/s12920-020-00855-1 |
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