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Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis

BACKGROUND: Variants in CDKN2B/CDKN2B-AS1 have been reported to modulate glaucoma risk in several GWAS across different populations. CDKN2B/CDKN2A encodes tumor suppressor proteins p16(INK4A)/p15(INK4B) which influences cell proliferation/senescence in RGCs, the degeneration of which is a risk facto...

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Detalles Bibliográficos
Autores principales: Thakur, Nanamika, Kupani, Manu, Mannan, Rashim, Pruthi, Archna, Mehrotra, Sanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780652/
https://www.ncbi.nlm.nih.gov/pubmed/33397358
http://dx.doi.org/10.1186/s12920-020-00855-1

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