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SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56

Meiosis creates genetic diversity by recombination and segregation of chromosomes. The synaptonemal complex assembles during meiotic prophase I and assists faithful exchanges between homologous chromosomes, but how its assembly/disassembly is regulated remains to be understood. Here, we report how t...

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Detalles Bibliográficos
Autores principales: Barbosa, Pedro, Zhaunova, Liudmila, Debilio, Simona, Steccanella, Verdiana, Kelly, Van, Ly, Tony, Ohkura, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780726/
https://www.ncbi.nlm.nih.gov/pubmed/33382409
http://dx.doi.org/10.1083/jcb.202009167