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Predicting the Disease Risk of Protein Mutation Sequences With Pre-training Model

Accurately identifying the missense mutations is of great help to alleviate the loss of protein function and structural changes, which might greatly reduce the risk of disease for tumor suppressor genes (e.g., BRCA1 and PTEN). In this paper, we propose a hybrid framework, called BertVS, that predict...

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Detalles Bibliográficos
Autores principales: Li, Kuan, Zhong, Yue, Lin, Xuan, Quan, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7780924/
https://www.ncbi.nlm.nih.gov/pubmed/33408741
http://dx.doi.org/10.3389/fgene.2020.605620

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