An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

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While genome-wide associations studies (GWAS) have successfully elucidated the genetic architecture of complex human traits and diseases, understanding mechanisms that lead from genetic variation to pathophysiology remains an important challenge. Methods are needed to systematically bridge this cruc...

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Detalles Bibliográficos
Autores principales: Wang, Liuyang, Balmat, Thomas J., Antonia, Alejandro L., Constantine, Florica J., Henao, Ricardo, Burke, Thomas W., Ingham, Andy, McClain, Micah T., Tsalik, Ephraim L., Ko, Emily R., Ginsburg, Geoffrey S., DeLong, Mark R., Shen, Xiling, Woods, Christopher W., Hauser, Elizabeth R., Ko, Dennis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781346/
https://www.ncbi.nlm.nih.gov/pubmed/33398303
http://dx.doi.org/10.1101/2020.12.20.20248572

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