Postpartum-Acquired Hemophilia A Presenting as Hemoperitoneum: A Case Report

Acquired hemophilia A (AHA) is a bleeding diathesis caused by the production of autoantibodies to factor VIII (FVIII). It manifests as an isolated deranged activated partial thromboplastin time (aPTT) indicating a defect in the intrinsic coagulation pathway. Herein, we report a case of a 26-year-old...

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Autores principales: Azam, Khalid, Batool, Zainab, Malik, Ayesha, Chaudhry, Manahil, Abdullah, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781504/
https://www.ncbi.nlm.nih.gov/pubmed/33409062
http://dx.doi.org/10.7759/cureus.11817
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author Azam, Khalid
Batool, Zainab
Malik, Ayesha
Chaudhry, Manahil
Abdullah, Mohammad
author_facet Azam, Khalid
Batool, Zainab
Malik, Ayesha
Chaudhry, Manahil
Abdullah, Mohammad
author_sort Azam, Khalid
collection PubMed
description Acquired hemophilia A (AHA) is a bleeding diathesis caused by the production of autoantibodies to factor VIII (FVIII). It manifests as an isolated deranged activated partial thromboplastin time (aPTT) indicating a defect in the intrinsic coagulation pathway. Herein, we report a case of a 26-year-old woman who presented with hemoperitoneum in the postpartum period following a lower segment Caesarean section (LSCS). AHA carries significant mortality if it remains undiagnosed, and early recognition and measures to eradicate the acquired inhibitors are the mainstays of its management.
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spelling pubmed-77815042021-01-05 Postpartum-Acquired Hemophilia A Presenting as Hemoperitoneum: A Case Report Azam, Khalid Batool, Zainab Malik, Ayesha Chaudhry, Manahil Abdullah, Mohammad Cureus Internal Medicine Acquired hemophilia A (AHA) is a bleeding diathesis caused by the production of autoantibodies to factor VIII (FVIII). It manifests as an isolated deranged activated partial thromboplastin time (aPTT) indicating a defect in the intrinsic coagulation pathway. Herein, we report a case of a 26-year-old woman who presented with hemoperitoneum in the postpartum period following a lower segment Caesarean section (LSCS). AHA carries significant mortality if it remains undiagnosed, and early recognition and measures to eradicate the acquired inhibitors are the mainstays of its management. Cureus 2020-12-01 /pmc/articles/PMC7781504/ /pubmed/33409062 http://dx.doi.org/10.7759/cureus.11817 Text en Copyright © 2020, Azam et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Azam, Khalid
Batool, Zainab
Malik, Ayesha
Chaudhry, Manahil
Abdullah, Mohammad
Postpartum-Acquired Hemophilia A Presenting as Hemoperitoneum: A Case Report
title Postpartum-Acquired Hemophilia A Presenting as Hemoperitoneum: A Case Report
title_full Postpartum-Acquired Hemophilia A Presenting as Hemoperitoneum: A Case Report
title_fullStr Postpartum-Acquired Hemophilia A Presenting as Hemoperitoneum: A Case Report
title_full_unstemmed Postpartum-Acquired Hemophilia A Presenting as Hemoperitoneum: A Case Report
title_short Postpartum-Acquired Hemophilia A Presenting as Hemoperitoneum: A Case Report
title_sort postpartum-acquired hemophilia a presenting as hemoperitoneum: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781504/
https://www.ncbi.nlm.nih.gov/pubmed/33409062
http://dx.doi.org/10.7759/cureus.11817
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AT chaudhrymanahil postpartumacquiredhemophiliaapresentingashemoperitoneumacasereport
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