Tissue specific diversification, virulence and immune response to Mycobacterium bovis BCG in a patient with an IFN-γ R1 deficiency

Summary: We characterized Mycobacterium bovis BCG isolates found in lung and brain samples from a previously vaccinated patient with IFNγR1 deficiency. The isolates collected displayed distinct genomic and phenotypic features consistent with host adaptation and associated changes in antibiotic susce...

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Detalles Bibliográficos
Autores principales: Korol, Cecilia B., Shallom, Shamira J., Arora, Kriti, Boshoff, Helena I., Freeman, Alexandra F., King, Alejandra, Agrawal, Sonia, Daugherty, Sean C., Jancel, Timothy, Kabat, Juraj, Ganesan, Sundar, Torrero, Marina N., Sampaio, Elizabeth P., Barry, Clifton, Holland, Steve M, Tettelin, Hervé, Rosenzweig, Sergio D, Zelazny, Adrian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781554/
https://www.ncbi.nlm.nih.gov/pubmed/33356838
http://dx.doi.org/10.1080/21505594.2020.1848108

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