Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature

Adamantinoma-like Ewing sarcoma (ALES) is a rare variant of Ewing sarcoma. It demonstrates heterogeneous morphologic pattern and complex immunophenotypic profile, with a peculiar combination of epithelial and neuroendocrine differentiation. ALES is rarely reported in the head and neck areas, includi...

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Autores principales: Alnuaim, Hala, Alzahrani, Malak, Ghandurah, Samirah, Dababo, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Endocrinology/Diabetes/Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781571/
https://www.ncbi.nlm.nih.gov/pubmed/33409103
http://dx.doi.org/10.7759/cureus.11870
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author Alnuaim, Hala
Alzahrani, Malak
Ghandurah, Samirah
Dababo, Mohammad
author_facet Alnuaim, Hala
Alzahrani, Malak
Ghandurah, Samirah
Dababo, Mohammad
author_sort Alnuaim, Hala
collection PubMed
description Adamantinoma-like Ewing sarcoma (ALES) is a rare variant of Ewing sarcoma. It demonstrates heterogeneous morphologic pattern and complex immunophenotypic profile, with a peculiar combination of epithelial and neuroendocrine differentiation. ALES is rarely reported in the head and neck areas, including the parotid salivary gland. Till now, only 10 cases of ALES have been reported in the salivary glands. Herein, we report two cases of ALES involving the parotid gland, adding some valuable insight to the recently reported cases at this site.
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spelling pubmed-77815712021-01-05 Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature Alnuaim, Hala Alzahrani, Malak Ghandurah, Samirah Dababo, Mohammad Cureus Endocrinology/Diabetes/Metabolism Adamantinoma-like Ewing sarcoma (ALES) is a rare variant of Ewing sarcoma. It demonstrates heterogeneous morphologic pattern and complex immunophenotypic profile, with a peculiar combination of epithelial and neuroendocrine differentiation. ALES is rarely reported in the head and neck areas, including the parotid salivary gland. Till now, only 10 cases of ALES have been reported in the salivary glands. Herein, we report two cases of ALES involving the parotid gland, adding some valuable insight to the recently reported cases at this site. Cureus 2020-12-03 /pmc/articles/PMC7781571/ /pubmed/33409103 http://dx.doi.org/10.7759/cureus.11870 Text en Copyright © 2020, Alnuaim et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Alnuaim, Hala
Alzahrani, Malak
Ghandurah, Samirah
Dababo, Mohammad
Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature
title Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature
title_full Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature
title_fullStr Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature
title_full_unstemmed Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature
title_short Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature
title_sort adamantinoma-like ewing sarcoma of the parotid gland: report of two cases and review of literature
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781571/
https://www.ncbi.nlm.nih.gov/pubmed/33409103
http://dx.doi.org/10.7759/cureus.11870
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