Novel PGC-1α/ATF5 Axis Partly Activates UPR(mt) and Mediates Cardioprotective Role of Tetrahydrocurcumin in Pathological Cardiac Hypertrophy

Mitochondrial unfolding protein response (UPR(mt)) effectively resists the pathological cardiac hypertrophy and improves the mitochondrial function. However, the specific activation mechanism and drugs that can effectively activate UPR(mt) in the cardiac muscle are yet to be elucidated. The aim of t...

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Detalles Bibliográficos
Autores principales: Zhang, Bing, Tan, Yanzhen, Zhang, Zhengbin, Feng, Pan, Ding, Wenyuan, Wang, Qian, Liang, Hongliang, Duan, Weixun, Wang, Xiaowu, Yu, Shiqiang, Liu, Jincheng, Yi, Dinghua, Sun, Yang, Yi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781724/
https://www.ncbi.nlm.nih.gov/pubmed/33425220
http://dx.doi.org/10.1155/2020/9187065

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