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Robust antigen-specific CD8 T cell tolerance to a model prostate cancer neoantigen

Immunotherapy has shown limited success in prostate cancer; this may be partially explained by its immunosuppressive tumor microenvironment (TME). Although androgen-deprivation therapy (ADT), the most common treatment for prostate cancer, initially promotes a robust T cell infiltrate, T cell respons...

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Detalles Bibliográficos
Autores principales:	Lopez-Bujanda, Zoila A., Chaimowitz, Matthew G., Armstrong, Todd D., Foote, Jeremy B., Emens, Leisha A., Drake, Charles G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781773/ https://www.ncbi.nlm.nih.gov/pubmed/33457094 http://dx.doi.org/10.1080/2162402X.2020.1809926

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