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Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India

OBJECTIVES: To describe the clinical and laboratory profile of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected neonates. METHODS: This is a review of hospital records, conducted in a tertiary care public hospital. Medical records of neonates born from 1 April, 2020 to 31 May, 2...

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Autores principales: Kalamdani, Pavan, Kalathingal, Thaslima, Manerkar, Swati, Mondkar, Jayashree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781822/
https://www.ncbi.nlm.nih.gov/pubmed/33043888
http://dx.doi.org/10.1007/s13312-020-2070-9
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author Kalamdani, Pavan
Kalathingal, Thaslima
Manerkar, Swati
Mondkar, Jayashree
author_facet Kalamdani, Pavan
Kalathingal, Thaslima
Manerkar, Swati
Mondkar, Jayashree
author_sort Kalamdani, Pavan
collection PubMed
description OBJECTIVES: To describe the clinical and laboratory profile of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected neonates. METHODS: This is a review of hospital records, conducted in a tertiary care public hospital. Medical records of neonates born from 1 April, 2020 to 31 May, 2020 were reviewed. Women admitted in labor were screened for SARS-CoV-2 infection based on the guidelines issued by Indian Council for Medical Research. Neonates were tested for SARS-CoV-2 infection once mother tested positive, which was after day 2 of life. Demographic, clinical features, laboratory tests and chest radiographs of SARS-CoV-2 infected neonates were reviewed and neonates were telephonically followed up till the age of 2 months. RESULTS: Out of 1229 mothers, 185 tested positive (15.05%); 12 neonates (6.48%) tested positive for SARS-CoV-2 infection. All neonates were exclusively breastfed. Symptoms, if any, were mild and self-limiting. Serum lactate dehydrogenase and liver enzymes were elevated. All neonates were healthy and thriving well on follow-up. CONCLUSION: SARS-CoV-2 infected neonates are mostly asymptomatic and thrive well on exclusive breastfeeding.
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spelling pubmed-77818222021-01-05 Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India Kalamdani, Pavan Kalathingal, Thaslima Manerkar, Swati Mondkar, Jayashree Indian Pediatr Research Paper OBJECTIVES: To describe the clinical and laboratory profile of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected neonates. METHODS: This is a review of hospital records, conducted in a tertiary care public hospital. Medical records of neonates born from 1 April, 2020 to 31 May, 2020 were reviewed. Women admitted in labor were screened for SARS-CoV-2 infection based on the guidelines issued by Indian Council for Medical Research. Neonates were tested for SARS-CoV-2 infection once mother tested positive, which was after day 2 of life. Demographic, clinical features, laboratory tests and chest radiographs of SARS-CoV-2 infected neonates were reviewed and neonates were telephonically followed up till the age of 2 months. RESULTS: Out of 1229 mothers, 185 tested positive (15.05%); 12 neonates (6.48%) tested positive for SARS-CoV-2 infection. All neonates were exclusively breastfed. Symptoms, if any, were mild and self-limiting. Serum lactate dehydrogenase and liver enzymes were elevated. All neonates were healthy and thriving well on follow-up. CONCLUSION: SARS-CoV-2 infected neonates are mostly asymptomatic and thrive well on exclusive breastfeeding. Springer India 2020-10-12 2020 /pmc/articles/PMC7781822/ /pubmed/33043888 http://dx.doi.org/10.1007/s13312-020-2070-9 Text en © Indian Academy of Pediatrics 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Paper
Kalamdani, Pavan
Kalathingal, Thaslima
Manerkar, Swati
Mondkar, Jayashree
Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India
title Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India
title_full Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India
title_fullStr Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India
title_full_unstemmed Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India
title_short Clinical Profile of SARS-CoV-2 Infected Neonates From a Tertiary Government Hospital in Mumbai, India
title_sort clinical profile of sars-cov-2 infected neonates from a tertiary government hospital in mumbai, india
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781822/
https://www.ncbi.nlm.nih.gov/pubmed/33043888
http://dx.doi.org/10.1007/s13312-020-2070-9
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