Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma

Placenta-specific 1 (PLAC1) is expressed primarily in placental trophoblasts but not in normal tissues and is a targetable candidate for cancer immunotherapy because it is a cancer testis antigen known to be up-regulated in various tumors. Although peptide epitopes capable of stimulating CD8 T cells...

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Detalles Bibliográficos
Autores principales: Hayashi, Ryusuke, Nagato, Toshihiro, Kumai, Takumi, Ohara, Kenzo, Ohara, Mizuho, Ohkuri, Takayuki, Hirata-Nozaki, Yui, Harabuchi, Shohei, Kosaka, Akemi, Nagata, Marino, Yajima, Yuki, Yasuda, Syunsuke, Oikawa, Kensuke, Kono, Michihisa, Kishibe, Kan, Takahara, Miki, Katada, Akihiro, Hayashi, Tatsuya, Celis, Esteban, Harabuchi, Yasuaki, Kobayashi, Hiroya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781841/
https://www.ncbi.nlm.nih.gov/pubmed/33457076
http://dx.doi.org/10.1080/2162402X.2020.1856545

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