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Anti-GD2 antibody and Vorinostat immunocombination therapy is highly effective in an aggressive orthotopic neuroblastoma model
Neuroblastoma is a childhood malignancy and in the majority of patients, the primary tumor arises in one of the adrenal glands. Neuroblastoma cells highly express the disialoganglioside GD2, which is the primary target for the development of neuroblastoma immunotherapy. Anti-GD2 mAbs have shown clin...
Autores principales: | van den Bijgaart, Renske J. E., Kroesen, Michiel, Brok, Ingrid C., Reijnen, Daphne, Wassink, Melissa, Boon, Louis, Hoogerbrugge, Peter M., Adema, Gosse J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781842/ https://www.ncbi.nlm.nih.gov/pubmed/33457098 http://dx.doi.org/10.1080/2162402X.2020.1817653 |
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