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Anti-inflammatory mechanisms of suppressors of cytokine signaling target ROS via NRF-2/thioredoxin induction and inflammasome activation in macrophages

Suppressors of cytokine signaling (SOCS) exhibit diverse anti-inflammatory effects. Since ROS acts as a critical mediator of inflammation, we have investigated the anti-inflammatory mechanisms of SOCS via ROS regulation in monocytic/macrophagic cells. Using PMA-differentiated monocytic cell lines an...

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Detalles Bibliográficos
Autores principales:	Kim, Ga-Young, Jeong, Hana, Yoon, Hye-Young, Yoo, Hye-Min, Lee, Jae Young, Park, Seok Hee, Lee, Choong-Eun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781909/ https://www.ncbi.nlm.nih.gov/pubmed/33172542 http://dx.doi.org/10.5483/BMBRep.2020.53.12.161

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