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MLL5, a histone modifying enzyme, regulates androgen receptor activity in prostate cancer cells by recruiting co-regulators, HCF1 and SET1

In prostate cancer, the androgen receptor (AR) transcription factor is a major regulator of cell proliferation and metastasis. To identify new AR regulators, we focused on Mixed lineage leukemia 5 (MLL5), a histone-regulating enzyme, because significantly higher MLL5 expression was detected in prost...

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Detalles Bibliográficos
Autores principales:	Lee, Kyoung-Hwa, Kim, Byung-Chan, Jeong, Chang Wook, Ku, Ja Hyeon, Kim, Hyeon Hoe, Kwak, Cheol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781910/ https://www.ncbi.nlm.nih.gov/pubmed/33050986 http://dx.doi.org/10.5483/BMBRep.2020.53.12.162

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