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Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA

Quantification of tumor‐specific variants (TSVs) in cell‐free DNA is rapidly evolving as a prognostic and predictive tool in patients with cancer. Currently, both variant allele frequency (VAF) and number of mutant molecules per mL plasma are used as units of measurement to report those TSVs. Howeve...

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Detalles Bibliográficos
Autores principales: Bos, Manouk K., Nasserinejad, Kazem, Jansen, Maurice P. H. M., Angus, Lindsay, Atmodimedjo, Peggy N., de Jonge, Evert, Dinjens, Winand N. M., van Schaik, Ron H. N., Del Re, Marzia, Dubbink, Hendrikus J., Sleijfer, Stefan, Martens, John W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782075/
https://www.ncbi.nlm.nih.gov/pubmed/33070443
http://dx.doi.org/10.1002/1878-0261.12827