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Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA
Quantification of tumor‐specific variants (TSVs) in cell‐free DNA is rapidly evolving as a prognostic and predictive tool in patients with cancer. Currently, both variant allele frequency (VAF) and number of mutant molecules per mL plasma are used as units of measurement to report those TSVs. Howeve...
Autores principales: | Bos, Manouk K., Nasserinejad, Kazem, Jansen, Maurice P. H. M., Angus, Lindsay, Atmodimedjo, Peggy N., de Jonge, Evert, Dinjens, Winand N. M., van Schaik, Ron H. N., Del Re, Marzia, Dubbink, Hendrikus J., Sleijfer, Stefan, Martens, John W. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782075/ https://www.ncbi.nlm.nih.gov/pubmed/33070443 http://dx.doi.org/10.1002/1878-0261.12827 |
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