BAP1 suppresses prostate cancer progression by deubiquitinating and stabilizing PTEN

Deubiquitinase BAP1 is an important tumor suppressor in several malignancies, but its functions and critical substrates in prostate cancer (PCa) remain unclear. Here, we report that the mRNA and protein expression levels of BAP1 are downregulated in clinical PCa specimens. BAP1 can physically bind t...

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Detalles Bibliográficos
Autores principales: Deng, Rong, Guo, Yanmin, Li, Lian, He, Jianfeng, Qiang, Zhe, Zhang, Hailong, Chen, Ran, Wang, Yanli, Zhao, Xian, Yu, Jianxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782096/
https://www.ncbi.nlm.nih.gov/pubmed/33155366
http://dx.doi.org/10.1002/1878-0261.12844

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