Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides

Sulphonamides and their isosteres are classical inhibitors of the carbonic anhydrase (CAs, EC 4.2.1.1) metalloenzymes. The protozoan pathogen Trichomonas vaginalis encodes two such enzymes belonging to the β-class, TvaCA1 and TvaCA2. Here we report the first sulphonamide inhibition study of TvaCA1,...

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Detalles Bibliográficos
Autores principales: Urbański, Linda J., Angeli, Andrea, Hytönen, Vesa P., Di Fiore, Anna, De Simone, Giuseppina, Parkkila, Seppo, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782162/
https://www.ncbi.nlm.nih.gov/pubmed/33356653
http://dx.doi.org/10.1080/14756366.2020.1863958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782162/
https://www.ncbi.nlm.nih.gov/pubmed/33356653
http://dx.doi.org/10.1080/14756366.2020.1863958

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