Cargando…

Synthesis, telomerase inhibitory and anticancer activity of new 2-phenyl-4H-chromone derivatives containing 1,3,4-oxadiazole moiety

Based on previous studies, 66 2-phenyl-4H-chromone derivatives containing amide and 1,3,4-oxadiazole moieties were prepared as potential telomerase inhibitors. The results showed most of the title compounds exhibited significantly inhibitory activity on telomerase. Among them, some compounds demonst...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Xu, Yu, Yun Long, Ma, Duo, Zhang, Zhao Yan, Liu, Xin Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782168/ https://www.ncbi.nlm.nih.gov/pubmed/33356666 http://dx.doi.org/10.1080/14756366.2020.1864630

Ejemplares similares

Synthesis and Antifungal Activity of Novel Sulfone Derivatives Containing 1,3,4-Oxadiazole Moieties
por: Xu, Weiming, et al.
Publicado: (2011)

Synthesis and Antibacterial Evaluation of Novel 1,3,4-Oxadiazole Derivatives Containing Sulfonate/Carboxylate Moiety
por: Wang, Lei, et al.
Publicado: (2020)

Synthesis and pesticidal activity of new 1,3,4-oxadiazole thioether compounds containing a trifluoromethylpyrazoyl moiety
por: Shi, Hai-Bo, et al.
Publicado: (2022)

Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives
por: Stecoza, Camelia Elena, et al.
Publicado: (2021)

Synthesis and Antibacterial Evaluation of New Sulfone Derivatives Containing 2-Aroxymethyl-1,3,4-Oxadiazole/Thiadiazole Moiety
por: Su, Shihu, et al.
Publicado: (2016)

Synthesis and Antioxidant Activity of 2-Amino-5-methylthiazol Derivatives Containing 1,3,4-Oxadiazole-2-thiol Moiety
por: Mohana, Kikkeri N., et al.
Publicado: (2013)

5-Phenyl-1,3,4-oxadiazol-2-amine
por: Song, Man-Man, et al.
Publicado: (2012)

Semisynthesis and insecticidal activity of some novel fraxinellone-based thioethers containing 1,3,4-oxadiazole moiety
por: Guo, Yong, et al.
Publicado: (2017)

2-[3,4-Dibutoxy-5-(5-phenyl-1,3,4-oxadiazol-2-yl)-2-thienyl]-5-phenyl-1,3,4-oxadiazole
por: Li, Hai-lin, et al.
Publicado: (2008)

Design, synthesis, insecticidal activity and 3D-QSR study for novel trifluoromethyl pyridine derivatives containing an 1,3,4-oxadiazole moiety
por: Xu, F. Z., et al.
Publicado: (2018)

Synthesis, Anticancer, Antimicrobial and Antioxidant Potential of Novel 4-(Substituted phenyl-1,3,4-oxadiazol/thiadiazol-2-yl)-4-(4-substituted phenyl) Azetidin-2-One Derivatives
por: Kumar, Davinder, et al.
Publicado: (2023)

Synthesis and In Vitro Antimicrobial Evaluation of New 1,3,4-Oxadiazoles Bearing 5-Chloro-2-methoxyphenyl Moiety
por: Prasanna Kumar, Basavapatna N., et al.
Publicado: (2013)

Novel 1,3,4-Oxadiazole Derivatives Containing a Cinnamic Acid Moiety as Potential Bactericide for Rice Bacterial Diseases
por: Wang, Shaobo, et al.
Publicado: (2019)

Antibacterial Activity and Mechanism of Action of Sulfone Derivatives Containing 1,3,4-Oxadiazole Moieties on Rice Bacterial Leaf Blight
por: Shi, Li, et al.
Publicado: (2015)

Synthesis and antifungal activities of novel nicotinamide derivatives containing 1,3,4-oxadiazole
por: Wu, Jian, et al.
Publicado: (2013)

2-Phenyl-5-(p-tolyl)-1,3,4-oxadiazole
por: Cordes, David B., et al.
Publicado: (2011)

Design, Synthesis and Anticonvulsant Activity of 2-(2-Phenoxy) phenyl- 1,3,4-oxadiazole Derivatives
por: Tabatabai, Sayyed Abbas, et al.
Publicado: (2013)

Design, Synthesis, In Vivo, and In Silico Evaluation of Benzothiazoles Bearing a 1,3,4-Oxadiazole Moiety as New Antiepileptic Agents
por: Chauhan, Bharti, et al.
Publicado: (2023)

Effects of pendant side groups on the properties of the silicon-containing arylacetylene resins with 2,5-diphenyl-[1,3,4]-oxadiazole moieties
por: Ma, Manping, et al.
Publicado: (2021)

1,3,4-Oxadiazole Contained Sesquiterpene Derivatives: Synthesis and Microbiocidal Activity for Plant Disease
por: Dai, Ali, et al.
Publicado: (2022)

Design, synthesis and in vitro antiproliferative activity of new thiazolidinedione-1,3,4-oxadiazole hybrids as thymidylate synthase inhibitors
por: Alzhrani, Zohor Mohammad Mahdi, et al.
Publicado: (2020)

Synthesis and Bioactivities of Novel Galactoside Derivatives Containing 1,3,4-Thiadiazole Moiety
por: Shu, Yafei, et al.
Publicado: (2022)

Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors
por: Xu, Ting, et al.
Publicado: (2022)

Synthesis and Anticancer Activity of N-Aryl-5-substituted-1,3,4-oxadiazol-2-amine Analogues
por: Ahsan, Mohamed Jawed, et al.
Publicado: (2014)

Synthesis, Characterization, and In Vitro Anticancer Evaluation of Novel 2,5-Disubstituted 1,3,4-Oxadiazole Analogue
por: Salahuddin,, et al.
Publicado: (2014)

Naproxen Based 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors: Design, Synthesis, Anticancer, and Computational Studies
por: Alam, Mohammad Mahboob, et al.
Publicado: (2021)

N-Phenyl-N-{4-[5-(4-pyridyl)-1,3,4-oxadiazol-2-yl]phenyl}aniline
por: Han, Li-Ping, et al.
Publicado: (2007)

Design, Synthesis, and Biological Activity of Novel Chalcone Derivatives Containing an 1,2,4-Oxadiazole Moiety
por: Luo, Ling, et al.
Publicado: (2022)

Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles
por: Aksenov, Alexander V., et al.
Publicado: (2019)

Ethyl 2-(5-phenyl-1,3,4-oxadiazol-2-ylsulfanyl)acetate
por: Zareef, Muhammad, et al.
Publicado: (2008)

2-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl acetate
por: dos Santos, Alexsandro F., et al.
Publicado: (2014)

Novel botanical active component derivatives containing carboxamide and 1,3,4-Thiadiazole thioether moieties: Design, synthesis, and inhibitory activity
por: Li, Pei, et al.
Publicado: (2022)

Synthesis, characterization, molecular docking, and anticancer activities of new 1,3,4-oxadiazole-5-fluorocytosine hybrid derivatives
por: El Mansouri, Az-eddine, et al.
Publicado: (2022)

Synthesis, molecular docking study and anticancer activity of novel 1,3,4-oxadiazole derivatives as potential tubulin inhibitors
por: Yousef, Tarek A., et al.
Publicado: (2023)

Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review
por: Wang, Jing-Jing, et al.
Publicado: (2022)

Synthesis, Characterization and Biological Activity Studies of 1,3,4-Oxadiazole Analogs
por: Bhat, KI, et al.
Publicado: (2011)

Antimicrobial Activity of 1,3,4-Oxadiazole Derivatives
por: Glomb, Teresa, et al.
Publicado: (2021)

2,5-Bis[2-(2-methoxyethoxy)phenyl]-1,3,4-oxadiazole
por: Tian, Xia, et al.
Publicado: (2009)

A facile synthesis and anticancer activity of some novel thiazoles carrying 1,3,4-thiadiazole moiety
por: Gomha, Sobhi M., et al.
Publicado: (2017)

5,5′-Di-4-pyridyl-2,2′-(p-phenylene)di-1,3,4-oxadiazole
por: Zhou, Rui-Sha, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_j77u3g2m94fkdo0jbvdgkd3n5b