Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote

Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-dementia Complex (ALS/PDC) is a disappearing neurodegenerative disease in three former high-incidence foci of the U.S. territory of Guam, Papua-Indonesia (New Guinea) and Kii Peninsula, Honshu Island, Japan (Muro disease). We report addi...

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Autores principales: Spencer, Peter S., Palmer, Valerie S., Kihira, Tameko, Yoshida, Sohei, Reis, Jacques, Yabushita, Momoko, Yase, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782320/
https://www.ncbi.nlm.nih.gov/pubmed/33426315
http://dx.doi.org/10.1016/j.ensci.2020.100308
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author Spencer, Peter S.
Palmer, Valerie S.
Kihira, Tameko
Yoshida, Sohei
Reis, Jacques
Yabushita, Momoko
Yase, Yoshiro
author_facet Spencer, Peter S.
Palmer, Valerie S.
Kihira, Tameko
Yoshida, Sohei
Reis, Jacques
Yabushita, Momoko
Yase, Yoshiro
author_sort Spencer, Peter S.
collection PubMed
description Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-dementia Complex (ALS/PDC) is a disappearing neurodegenerative disease in three former high-incidence foci of the U.S. territory of Guam, Papua-Indonesia (New Guinea) and Kii Peninsula, Honshu Island, Japan (Muro disease). We report additional data that associate medicinal use of cycad seed to Muro disease in the southern Kozagawa focus of ALS/PDC. In the other two ALS/PDC-affected populations, cycad seed was used as a traditional topical medicine in New Guinea and Guam and, additionally, for food on Guam.
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spelling pubmed-77823202021-01-08 Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote Spencer, Peter S. Palmer, Valerie S. Kihira, Tameko Yoshida, Sohei Reis, Jacques Yabushita, Momoko Yase, Yoshiro eNeurologicalSci Letter to the Editor Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-dementia Complex (ALS/PDC) is a disappearing neurodegenerative disease in three former high-incidence foci of the U.S. territory of Guam, Papua-Indonesia (New Guinea) and Kii Peninsula, Honshu Island, Japan (Muro disease). We report additional data that associate medicinal use of cycad seed to Muro disease in the southern Kozagawa focus of ALS/PDC. In the other two ALS/PDC-affected populations, cycad seed was used as a traditional topical medicine in New Guinea and Guam and, additionally, for food on Guam. Elsevier 2020-12-25 /pmc/articles/PMC7782320/ /pubmed/33426315 http://dx.doi.org/10.1016/j.ensci.2020.100308 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Letter to the Editor
Spencer, Peter S.
Palmer, Valerie S.
Kihira, Tameko
Yoshida, Sohei
Reis, Jacques
Yabushita, Momoko
Yase, Yoshiro
Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote
title Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote
title_full Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote
title_fullStr Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote
title_full_unstemmed Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote
title_short Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote
title_sort kampō medicine and muro disease (amyotrophic lateral sclerosis and parkinsonism-dementia complex): postscript and historical footnote
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782320/
https://www.ncbi.nlm.nih.gov/pubmed/33426315
http://dx.doi.org/10.1016/j.ensci.2020.100308
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