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TLR agonists enhance responsiveness of inflammatory innate immune cells in HLA-B*57-positive HIV patients

ABSTRACT: HLA-B*57 affects the course of HIV infection. Under antiretroviral therapy, its effects cannot be explained by outstandingly efficient T cell responses alone but may also involve cells of innate immunity. Studying in vitro stimulation with Pam3CSK4, E. coli LPS-B5 and CpG-ODN-2216, we obse...

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Detalles Bibliográficos
Autores principales: Dold, L., Zimmer, L., Schwarze-Zander, C., Boesecke, C., Mohr, R., Wasmuth, J.-C., Ommer, K., Gathof, B., Krämer, B., Nattermann, J., Strassburg, C. P., Rockstroh, J. K., Spengler, U., Langhans, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782382/
https://www.ncbi.nlm.nih.gov/pubmed/33278000
http://dx.doi.org/10.1007/s00109-020-01996-7