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Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance

The effective storage of lipids in white adipose tissue (WAT) critically impacts whole body energy homeostasis. Many genes have been implicated in WAT lipid metabolism, including tripartite motif containing 28 (Trim28), a gene proposed to primarily influence adiposity via epigenetic mechanisms in em...

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Detalles Bibliográficos
Autores principales:	Bond, Simon T., King, Emily J., Henstridge, Darren C., Tran, Adrian, Moody, Sarah C., Yang, Christine, Liu, Yingying, Mellett, Natalie A., Nath, Artika P., Inouye, Michael, Tarling, Elizabeth J., de Aguiar Vallim, Thomas Q., Meikle, Peter J., Calkin, Anna C., Drew, Brian G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782476/ https://www.ncbi.nlm.nih.gov/pubmed/33397965 http://dx.doi.org/10.1038/s41467-020-20434-3

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