ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1

Inflammation and cell death are closely linked arms of the host immune response to infection, which when carefully balanced ensure host survival. One example of this balance is the tightly regulated transition from TNFR1-associated pro-inflammatory complex I to pro-death complex II. By contrast, her...

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Detalles Bibliográficos
Autores principales: Muendlein, Hayley I., Connolly, Wilson M., Magri, Zoie, Smirnova, Irina, Ilyukha, Vladimir, Gautam, Avishekh, Degterev, Alexei, Poltorak, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782486/
https://www.ncbi.nlm.nih.gov/pubmed/33397971
http://dx.doi.org/10.1038/s41467-020-20357-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782486/
https://www.ncbi.nlm.nih.gov/pubmed/33397971
http://dx.doi.org/10.1038/s41467-020-20357-z

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