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Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

SOX (SRY-related HMG-box) transcription factors perform critical functions in development and cell differentiation. These roles depend on precise nuclear trafficking, with mutations in the nuclear targeting regions causing developmental diseases and a range of cancers. SOX protein nuclear localizati...

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Detalles Bibliográficos
Autores principales:	Jagga, Bikshapathi, Edwards, Megan, Pagin, Miriam, Wagstaff, Kylie M., Aragão, David, Roman, Noelia, Nanson, Jeffrey D., Raidal, Shane R., Dominado, Nicole, Stewart, Murray, Jans, David A., Hime, Gary R., Nicolis, Silvia K., Basler, Christopher F., Forwood, Jade K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782513/ https://www.ncbi.nlm.nih.gov/pubmed/33397924 http://dx.doi.org/10.1038/s41467-020-20194-0

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