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A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

Aberrant soluble oligomers formed by the amyloid-β peptide (Aβ) are major pathogenic agents in the onset and progression of Alzheimer’s disease. A variety of biomolecules can influence the formation of these oligomers in the brain, although their mechanisms of action are still largely unknown. Here,...

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Detalles Bibliográficos
Autores principales: Cataldi, Rodrigo, Chia, Sean, Pisani, Katarina, Ruggeri, Francesco S., Xu, Catherine K., Šneideris, Tomas, Perni, Michele, Sarwat, Sunehera, Joshi, Priyanka, Kumita, Janet R., Linse, Sara, Habchi, Johnny, Knowles, Tuomas P. J., Mannini, Benedetta, Dobson, Christopher M., Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782527/
https://www.ncbi.nlm.nih.gov/pubmed/33398040
http://dx.doi.org/10.1038/s42003-020-01490-3