Cargando…
Identification of PIM1 substrates reveals a role for NDRG1 phosphorylation in prostate cancer cellular migration and invasion
PIM1 is a serine/threonine kinase that promotes and maintains prostate tumorigenesis. While PIM1 protein levels are elevated in prostate cancer relative to local disease, the mechanisms by which PIM1 contributes to oncogenesis have not been fully elucidated. Here, we performed a direct, unbiased che...
Autores principales: | Ledet, Russell J., Ruff, Sophie E., Wang, Yu, Nayak, Shruti, Schneider, Jeffrey A., Ueberheide, Beatrix, Logan, Susan K., Garabedian, Michael J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782530/ https://www.ncbi.nlm.nih.gov/pubmed/33398037 http://dx.doi.org/10.1038/s42003-020-01528-6 |
Ejemplares similares
-
PIM1 phosphorylation of the androgen receptor and 14-3-3 ζ regulates gene transcription in prostate cancer
por: Ruff, Sophie E., et al.
Publicado: (2021) -
Phosphorylation of the Androgen Receptor by PIM1 in Hormone Refractory Prostate Cancer
por: Ha, Susan, et al.
Publicado: (2012) -
mTOR Regulation of N-Myc Downstream Regulated 1 (NDRG1) Phosphorylation in Clear Cell Renal Cell Carcinoma
por: Valluri, Anisha, et al.
Publicado: (2023) -
Insulin receptor substrate 1 is a substrate of the Pim protein kinases
por: Song, Jin H., et al.
Publicado: (2016) -
Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer’s disease brain tissue
por: Drummond, Eleanor S, et al.
Publicado: (2015)