Cargando…

Differential transcript usage unravels gene expression alterations in Alzheimer’s disease human brains

Alzheimer’s disease (AD) is the leading cause of dementia in aging individuals. Yet, the pathophysiological processes involved in AD onset and progression are still poorly understood. Among numerous strategies, a comprehensive overview of gene expression alterations in the diseased brain could contr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marques-Coelho, Diego, Iohan, Lukas da Cruz Carvalho, Melo de Farias, Ana Raquel, Flaig, Amandine, Lambert, Jean-Charles, Costa, Marcos Romualdo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782705/ https://www.ncbi.nlm.nih.gov/pubmed/33398016 http://dx.doi.org/10.1038/s41514-020-00052-5

Ejemplares similares

Analysis of modular gene co-expression networks reveals molecular pathways underlying Alzheimer’s disease and progressive supranuclear palsy
por: Iohan, Lukas da Cruz Carvalho, et al.
Publicado: (2022)

Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons
por: Melo de Farias, Ana Raquel, et al.
Publicado: (2023)

Pyk2 overexpression in postsynaptic neurons blocks amyloid β(1–42)-induced synaptotoxicity in microfluidic co-cultures
por: Kilinc, Devrim, et al.
Publicado: (2020)

Unravelling the mechanotransduction pathways in Alzheimer’s disease
por: Donnaloja, Francesca, et al.
Publicado: (2023)

Sisyphus observed: Unraveling the high ATP usage of an RNA chaperone
por: Duran, Elizabeth C., et al.
Publicado: (2021)

Novel Exosome Biomarker Candidates for Alzheimer’s Disease Unravelled Through Mass Spectrometry Analysis
por: Soares Martins, Tânia, et al.
Publicado: (2022)

Lineage Reprogramming of Astroglial Cells from Different Origins into Distinct Neuronal Subtypes
por: Chouchane, Malek, et al.
Publicado: (2017)

Unraveling Alzheimer’s: Making Sense of the Relationship between Diabetes and Alzheimer’s Disease(1)
por: Schilling, Melissa A.
Publicado: (2016)

acorde unravels functionally interpretable networks of isoform co-usage from single cell data
por: Arzalluz-Luque, Angeles, et al.
Publicado: (2022)

Unravelling the diversity in water usage among wild banana species in response to vapour pressure deficit
por: Eyland, David, et al.
Publicado: (2023)

A Bioinformatics Approach Toward Unravelling the Synaptic Molecular Crosstalk Between Alzheimer’s Disease and Diabetes
por: Alves, Steven R., et al.
Publicado: (2022)

Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer?
por: Kovacs, Gabor G.
Publicado: (2016)

Unraveling the genetic complexity of Alzheimer disease with Mendelian Randomization
por: Bandres-Ciga, Sara, et al.
Publicado: (2019)

Parental perception of FIRES outcomes, emotional states, and social media usage
por: Farias‐Moeller, Raquel, et al.
Publicado: (2021)

The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects
por: Lambert, Erwan, et al.
Publicado: (2022)

Unraveling the Black Box: Exploring Usage Patterns of a Blended Treatment for Depression in a Multicenter Study
por: Kemmeren, Lise L, et al.
Publicado: (2019)

Unraveling the dynamics of the Omicron and Delta variants of the 2019 coronavirus in the presence of vaccination, mask usage, and antiviral treatment
por: Ngonghala, Calistus N., et al.
Publicado: (2023)

Unraveling the effect of gender dimensions and wood fuel usage on household food security: evidence from Ghana
por: Adjei-Mantey, Kwame, et al.
Publicado: (2022)

Microbiome Alterations and Alzheimer’s Disease: Modeling Strategies with Transgenic Mice
por: López-Villodres, Juan Antonio, et al.
Publicado: (2023)

Untargeted metabolomics unravel serum metabolic alterations in smokers with hypertension
por: Shen, Yang, et al.
Publicado: (2023)

Deciphering cellular transcriptional alterations in Alzheimer’s disease brains
por: Wang, Xue, et al.
Publicado: (2020)

Cellular transcriptional alterations of peripheral blood in Alzheimer’s disease
por: Song, Liting, et al.
Publicado: (2022)

CSF β-amyloid and white matter damage: unravelling the neuropathology of Alzheimer’s disease
por: Sousa Alves, Gilberto
Publicado: (2018)

Unraveling the Gordian knot: genetics and the troubled road to effective therapeutics for Alzheimer’s disease
por: Restifo, Linda L
Publicado: (2021)

Unraveling the Binding Mechanism of Alzheimer’s Drugs with Irisin: Spectroscopic, Calorimetric, and Computational Approaches
por: Waseem, Rashid, et al.
Publicado: (2022)

Alteration of synonymous codon usage bias accompanies polyploidization in wheat
por: Tian, Geng, et al.
Publicado: (2022)

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis
por: Bonnier, Guillaume, et al.
Publicado: (2014)

Unravelling the Enigma: How Behavioural Addictions Alter the Developing Child Brain?
por: Pandey, Manoj K., et al.
Publicado: (2023)

Editorial: Unravelling Citrus Huanglongbing Disease
por: Ferrarezi, Rhuanito Soranz, et al.
Publicado: (2020)

Unraveling the potential co-contributions of cerebral small vessel vasculopathy to the pathogenesis of Alzheimer’s dementia
por: Edwards, Jodi D., et al.
Publicado: (2015)

Unravelling the Role of Glycogen Synthase Kinase-3 in Alzheimer’s Disease-Related Epileptic Seizures
por: Lin, Runxuan, et al.
Publicado: (2020)

Microfluidic Platforms to Unravel Mysteries of Alzheimer’s Disease: How Far Have We Come?
por: Prasanna, Pragya, et al.
Publicado: (2021)

Biomarker Candidates for Alzheimer’s Disease Unraveled through In Silico Differential Gene Expression Analysis
por: Silva-Lucero, Maria-del-Carmen, et al.
Publicado: (2022)

Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2
por: Guimarães, Roberta Pereira de Melo, et al.
Publicado: (2018)

Unraveling the molecular basis of host cell receptor usage in SARS-CoV-2 and other human pathogenic β-CoVs
por: Pontes, Camila, et al.
Publicado: (2021)

Transcriptional Alterations Related to Neuropathology and Clinical Manifestation of Alzheimer’s Disease
por: Silva, Aderbal R. T., et al.
Publicado: (2012)

Correction to: Deciphering cellular transcriptional alterations in Alzheimer’s disease brains
por: Wang, Xue, et al.
Publicado: (2020)

Unraveling Hepatic Metabolomic Profiles and Morphological Outcomes in a Hybrid Model of NASH in Different Mouse Strains
por: Bacil, Gabriel P., et al.
Publicado: (2023)

Leveraging phylogenetic signal to unravel microbiome function and assembly rules
por: Talavera-Marcos, Silvia, et al.
Publicado: (2023)

Enhancer dynamics: Unraveling the mechanism of transcriptional bursting
por: Fukaya, Takashi
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3mgrm7vtuqffdfs3lnn5pidcqd