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Filamentous recombinant human Tau activates primary astrocytes via an integrin receptor complex
Microtubule-associated protein Tau can form protein aggregates transmissible within the brain, correlating with the progression of tauopathies in humans. The transmission of aggregates requires neuron-released Tau to interact with surface receptors on target cells. However, the underlying molecular...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782792/ https://www.ncbi.nlm.nih.gov/pubmed/33398028 http://dx.doi.org/10.1038/s41467-020-20322-w |