Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases

Histones control gene expression by regulating chromatin structure and function. The posttranslational modifications (PTMs) on the side chains of histones form the epigenetic landscape, which is tightly controlled by epigenetic modulator enzymes and further recognized by so-called reader domains. Hi...

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Detalles Bibliográficos
Autores principales: Moreno-Yruela, Carlos, Bæk, Michael, Vrsanova, Adela-Eugenie, Schulte, Clemens, Maric, Hans M., Olsen, Christian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782793/
https://www.ncbi.nlm.nih.gov/pubmed/33397936
http://dx.doi.org/10.1038/s41467-020-20250-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782793/
https://www.ncbi.nlm.nih.gov/pubmed/33397936
http://dx.doi.org/10.1038/s41467-020-20250-9

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