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Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases
Histones control gene expression by regulating chromatin structure and function. The posttranslational modifications (PTMs) on the side chains of histones form the epigenetic landscape, which is tightly controlled by epigenetic modulator enzymes and further recognized by so-called reader domains. Hi...
Autores principales: | Moreno-Yruela, Carlos, Bæk, Michael, Vrsanova, Adela-Eugenie, Schulte, Clemens, Maric, Hans M., Olsen, Christian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782793/ https://www.ncbi.nlm.nih.gov/pubmed/33397936 http://dx.doi.org/10.1038/s41467-020-20250-9 |
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