Pharmacological blockage of transforming growth factor-β signalling by a Traf2- and Nck-interacting kinase inhibitor, NCB-0846

BACKGROUND: Metastasis is the primary cause of death in cancer patients, and its management is still a major challenge. Epithelial to mesenchymal transition (EMT) has been implicated in the process of cancer metastasis, and its pharmacological interference holds therapeutic promise. METHODS: Traf2-...

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Detalles Bibliográficos
Autores principales: Sugano, Teppei, Masuda, Mari, Takeshita, Fumitaka, Motoi, Noriko, Hirozane, Toru, Goto, Naoko, Kashimoto, Shigeki, Uno, Yuko, Moriyama, Hideki, Sawa, Masaaki, Nagakawa, Yuichi, Tsuchida, Akihiko, Seike, Masahiro, Gemma, Akihiko, Yamada, Tesshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782820/
https://www.ncbi.nlm.nih.gov/pubmed/33244122
http://dx.doi.org/10.1038/s41416-020-01162-3

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