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Divergent Evolution of a Protein–Protein Interaction Revealed through Ancestral Sequence Reconstruction and Resurrection

The postsynaptic density extends across the postsynaptic dendritic spine with discs large (DLG) as the most abundant scaffolding protein. DLG dynamically alters the structure of the postsynaptic density, thus controlling the function and distribution of specific receptors at the synapse. DLG contain...

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Detalles Bibliográficos
Autores principales: Laursen, Louise, Čalyševa, Jelena, Gibson, Toby J, Jemth, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782867/
https://www.ncbi.nlm.nih.gov/pubmed/32750125
http://dx.doi.org/10.1093/molbev/msaa198