Response to: The mitochondria-targeted antioxidant MitoQ attenuates exercise-induced mitochondrial DNA damage (Williamson et al., available online 6 August 2020, 101,673)

Williamson and colleagues present important data on the effects of MitoQ - an antioxidant compound targeted to mitochondria - on mtDNA damage following exercise. Future studies are needed to elucidate, whether or not the observed prevention of MitoQ on DNA damage is beneficial with regard to functio...

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Detalles Bibliográficos
Autores principales: Burtscher, Johannes, Burtscher, Martin, Millet, Grégoire P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782926/
https://www.ncbi.nlm.nih.gov/pubmed/32980310
http://dx.doi.org/10.1016/j.redox.2020.101732
Descripción
Sumario:Williamson and colleagues present important data on the effects of MitoQ - an antioxidant compound targeted to mitochondria - on mtDNA damage following exercise. Future studies are needed to elucidate, whether or not the observed prevention of MitoQ on DNA damage is beneficial with regard to functional outcomes in healthy, exercising humans in dependence of the exercise stimulus and individual characteristics of the person.

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